Main Article Content

Abstract

Diabetes Mellitus (DM) is a group of metabolic diseases with hyperglycemia characteristics that can lead to  kidney complications. One of them is Diabetic Nephropathy which is a complication of microvascular damage and its monitoring is done by checking serum creatinine and creatinine clearance test (CCT). The purpose of this study was to determine the relationship between serum creatinine levels and creatinine clearance test (CCT) in patients with type 2 DM. Perform a serum creatinine examination which is used as the basis for calculating CCT. From 53 data on type 2 DM patients who had high serum creatinine levels, 49 (92.5%) people, 51 (96.2%) people with low CCT levels. The results of Spearman's correlation statistical test showed a correlation between serum creatinine levels and CCT. The strength of the correlation is moderate, and the correlation shows a negative direction with a correlation coefficient (r) of -0.389. It can be concluded that the higher the serum creatinine level, the lower the CCT value, so DM patients must control blood glucose regularly in order to prevent a decrease in kidney function that can lead to complications.

Keywords

Creatinine Creatinine Clearance Test (CCT) Type-2 Diabetes Mellitus

Article Details

How to Cite
Prasetyorini, T., Lestari, D., Anzalinna, A., & Suratun, S. (2022). Profile of Serum Creatinine Levels with Creatinine Clearance Test (CCT) of Patients with Type 2 Diabetes Mellitus at Budhi Asih Hospital in 2021. Jurnal Ilmu Dan Teknologi Kesehatan, 10(1), 25-35. https://doi.org/10.32668/jitek.v10i1.865

References

    Aditya, A. et al. (2018) ‘Screening Fungsi Ginjal Sebagai Perbaikan Outcome Pengobatan Pada Penderita Diabetes Mellitus Tipe Ii (Studi Di Wilayah Kerja Puskesmas Ngesrep)’, Jurnal Kesehatan Masyarakat (e-Journal), 6(1), pp. 191–199.

    Alternative, C. and Description, N. (2012) ‘Creatinine ( serum , plasma )’, pp. 3–7.

    Bhatt, H., Saklani, S. and Upadhayay, K. (2016) ‘Anti-oxidant and anti-diabetic activities of ethanolic extract of Primula Denticulata Flowers’, Indonesian Journal of Pharmacy, 27(2), pp. 74–79. doi:10.14499/indonesianjpharm27iss2pp74.

    Fera Sartika, Dwi Purbayanti, D.S. (2018) ‘Gambaran Laju Filtrasi Glomerulus Pada Penderita Diabetes Melitus Tipe 2 RSUD DR. Doris Sylvanus Palangka Raya’, 3(2), pp. 13–21.

    Hardyati, A. (2019) ‘Infeksi Saluran Kemih Pada Pasien Diabetes Mellitus Di Rsud Budhi Asih Jakarta Timur’, Jurnal Ilmiah Kesehatan, 10(2), pp. 199–204. doi:10.37012/jik.v10i2.55.

    Indrasari, D.N. (2015) ‘Perbedaan Kadar Ureum Dan Kreatinin Pada Pasien Gagal Ginjal Kronik Berdasarkan Lama Menjalani Terapi Hemodialisa Di RS PKU Muhammadiyah Yogyakarta: Naskah Publikasi’, Jurnal keperawatan STIKES ’Aisyiyah Yogyakarta [Preprint].

    Indriani, V., Siswandari, W. and Lestari, T. (2017) ‘Hubungan antara kadar ureum, kreatinin dan klirens kreatinin dengan proteinuria pada penderita diabetes mellitus’, Prosiding, 7(1).

    Joddy, R. et al. (2017) ‘Kejadian Efek Samping Potensial Terapi Obat Anti Diabetes Pasien Diabetes Melitus Berdasarkan Algoritma Naranjo Potential Side Effects of Anti-Diabetic Drug Therapy In Diabetes Mellitus Patients Based On Naranjo Algorithm’, 2(2), pp. 45–50.

    Martini., Nur W, E. and Mutalazimah (2010) ‘Hubungan Tingkat Asupan Protein Dengan Kadar Ureum Dan Kreatinin Darah Pada Penderita Gagal Kronik DI RSUD Dr. Moewardi Surakarta’, Jurnal Kesehatan, 3(1), pp. 19–26.

    Meidikayanti, W. and Wahyuni, C.U. (2017) ‘Hubungan Dukungan Keluarga dengan Kualitas Hidup Diabetes Melitus Tipe 2’, Jurnal Berkala Epidemiologi, 5(2), pp. 240–252. doi:10.20473/jbe.v5i2.2017.240-252.

    Nur, R. (2020) Korelasi Antara Kadar HbA1c Dengan Laju Filtrasi Glomerulus (LFG) Pada Penerita Diabetes Melitus Di RSUD Budhi Asih Jakarta Timur.

    PERKENI (2015) ‘Konsensus Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2’, Dissertation Abstracts International Section A: Humanities and Social Sciences, 71(2-A), p. 730.

    Purnamasari, E. and Poerwantoro, B. (2011) ‘Diabetes Mellitus dengan Penyulit Kronis’, Majalah Kesehatan PharmaMedika, 3(2), pp. 276–281.

    Restada, E.J. (2016) ‘Hubungan lama menderita dan komplikasi diabetes melitus dengan kualitas hidup pada penderita diabetes melitus di wilayah Puskesmas Gatak Sukoharjo’, Skripsi. Program Studi S1 Keperawatan Fakultas Ilmu Kesehatan Universitas Muhammadiyah Surakarta [Preprint].

    Rivandi, J. and Yonata, A. (2015) ‘Hubungan Diabetes Melitus Dengan Kejadian Gagal Ginjal Kronik’, Jurnal Majority, 4(9), pp. 27–34.

    Salman Alfarisi, Wiranto Basuki, T.S. (2012) ‘Perbedaan Kadar Kreatinin Serum Pasien Diabetes Melitus Tipe 2 Yang Terkontrol Dengan Yang Tidak Terkontrol Di Rsud Dr . H . Abdul Moeloek Differences in Serum Creatinine Levels of Type 2 Diabetes Mellitus Patient That Controlled With Not Controlled in Dr’, pp. 129–136.

    Samodro, P., Hernayanti, H. and Prastowo, A. (2016) ‘Kadar C-Reactive Protein dan Laju Filtrasi Glomerulus Pasien Diabetes Melitus Tipe 2 Obesitas di RSUD Margono Soekarjo Purwokerto’, JURNAL NUTRISIA, 18(2), pp. 93–98.

    Santosa, A., Trijayanto, P.A. and Endiyanto (2017) ‘Hubungan Riwayat Garis Keturunan dengan Usia Terdiagnosis Diabetes Melitus Tipe II’, Jurnal Ilmiah Kesehatan, pp. 1–6.

    Soelistijo, S. et al. (2015) Konsesus Pengelolaan Dan Pencegahan Diabetes Melitus Tipe2 Di Indonesia 2015, Perkeni.

    Suryawan, D.G.A., Arjani, I.A.M.S. and I G Sudarmanto (2016) ‘Gambaran Kadar Ureum Dan Kreatinin Serum pada Pasien Gagal Ginjal Kronis yang Menjalani Terapi Hemodialisis di RSUD Sanjiwani Gianyar’, Meditory, 4(1), pp. 145–153.

    Trihartati, V. (2019) ‘Gambaran Kadar Ureum dan Kreatinin Serum pada Pasien Diabetes Melitus Tipe-2 di Rumah Sakit Santa Maria Pekanbaru’, Jurnal Sains dan Teknologi Laboratorium Medik, 4(2), pp. 44–53.

    WHO (2018) ‘Global Burden of Diabetes; Global Report on Diabetes’, p. 88.