Article Sidebar

Published
Sep 30, 2022
Download
pdf
Statistic
Read Counter : 432 Download : 306

Main Article Content

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Pulmonary TB has become a health problem worldwide, including in Indonesia, because the sufferers' prevalence is increasing every year. The increase in TB drug resistance will pose a severe health threat. The continuous consumption of drugs in large quantities and high doses can affect the function of the thyroid gland. This study aimed to determine the levels of thyroid stimulating hormone (TSH) in pulmonary tuberculosis patients with treatment phases of 0 months and six months. This research is analytical observational research with a cross-sectional research design. The sampling method uses accidental sampling. A total of 42 respondents participated in this study to determine the levels of TSH in pulmonary TB. The results of the Mann-Whitney U test showed no difference in TSH levels in pulmonary TB patients with different treatment phases of 0 months and six months (p = 0.3). There was no significant difference between TSH levels in pulmonary TB patients in the 0 and 6-month treatment phases.

Keywords

pulmonary tuberculosis thyroid stimulating hormone TSH Mycobacterium tuberculosis

Article Details

Authors who publish with this journal agree to the following terms:

1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.

2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.

3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

Author Biography

Dita Pratiwi Kusuma Wardani, Muhammadiyah University of Purwokerto, Indonesia

PRODI TEKNOLOGI LABORATORIUM MEDIK D4

How to Cite
Qo’imah, A., Wardani, D., Sudarsono, T., & Mulyanto, A. (2022). Comparison of TSH Levels Pulmonary Tuberculosis Patients at The Phase 0 and 6 Months Treatment. Jurnal Ilmu Dan Teknologi Kesehatan, 10(1), 99-107. https://doi.org/10.32668/jitek.v10i1.910

References

    Absor, S. et al. (2020) ‘Hubungan Tingkat Pendidikan Dengan Kepatuhan Berobat Penderita Tb Paru Di Wilayah Kabupaten Lamongan Pada Januari 2016 – Desember 2018’, Medica Arteriana (Med-Art), 2(2), p. 80. doi: 10.26714/medart.2.2.2020.80-87.

    Adnan, M. (2021) ‘ASUHAN GIZI PADA HIPOTIROID Nutritional Care On Hypothyroid Miftahul Adnan Universitas Muhammadiyah Semarang’, 9(1), pp. 19–24.

    Adyaningrum, N., Suryawati, C. and Budiyanti, R. T. (2019) ‘Analisis Pengawasan Menelan Obat Pasien Tuberkulosis (TB) Dalam Program Penanggulangan TB di Puskesmas Sempor II Kabupaten Kebumen’, Jurnal Kesehatan Masyarakat (e-Journal), 7(4), pp. 542–555.

    AIM (2019) AIM TSH Q Rapid Test. Jakarta: PT. Akurat Intan Madya.

    Andries, A. et al. (2013). 'High Rate of Hypothyroidism in Multidrug-Resistant Tuberculosis Patients Co-Infected with HIV in Mumbai, India, PLoS ONE, 8(10), pp. 1–7. DOI: 10.1371/journal.pone.0078313.

    Biranu, E. et al. (2021). 'Thyroid profile and factors associated with hypothyroidism among multidrug-resistant tuberculosis patients attending saint peter's specialized hospital Addis Ababa, Ethiopia, Infection and Drug Resistance, 14(June), pp. 2675–2684. doi: 10.2147/IDR.S310404.

    Dash, M., Behera, B. P. and Sen, R. K. (2020). 'Thyroid profile in pulmonary tuberculosis patients: a prospective study in a tertiary medical college of southern Odisha', International Journal of Clinical Trials, 7(2), p. 66. doi: 10.18203/2349-3259.ijct20200538.

    Dasopang, E. S., Hasanah, F. and Nisak, C. (2019) ‘Analisis Deskriptif Efek Samping Penggunaan Obat Anti Tuberculosis Pada Pasien TBC di RSUD Dr. Pirngadi Medan’, Jurnal Penelitian Farmasi & Herbal, 2(1), pp. 44–49. doi: 10.36656/jpfh.v2i1.180.

    Devalraju, K. P. et al. (2021). 'Reduced thyroxine production in young household contacts of tuberculosis patients increases active tuberculosis disease risk, JCI Insight, 6(13), pp. 1–17. DOI: 10.1172/jci.insight.148271.

    Fitriani, N. E., Sinaga, T. and Syahran, A. (2020) ‘Hubungan Antara Pengetahuan, Motivasi Pasien dan Dukungan Keluarga Terhadap Kepatuhan Minum Obat Anti Tuberkulosis (OAT) Pada Penderita Penyakit TB Paru BTA (+) di Puskesmas Pasundan Kota Samarinda’, KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat, 5(2), p. 124. doi: 10.24903/kujkm.v5i2.838.

    Hadifah, Z., Subronto, Y. W. and Ikhsan, M. R. (2019) ‘Faktor Risiko Gagal Konversi BTA pada Pasien Tuberkulosis Paru Fase Intensif di Kota Yogyakarta’, Buletin Penelitian Kesehatan, 47(2), pp. 83–88. doi: 10.22435/bpk.v47i2.1002.

    Hamza, D. H. and Sabee, K. M. (2016). 'The Effect of pulmonary tuberculosis and short course treatment on some hormones of patients women’, Muthanna Medical Journal, 3(2), pp. 139–146.

    Hutama, R. K. (2019) ‘Gambaran Perilaku Penderita Tb Paru Dalam Pencegahan Penularan Tb Paru Di Kabupaten Klaten’, Jurnal Kesehatan Masyarakat (e-Journal), 7(1), pp. 491–500.

    Ige, O. M. et al. (2016). 'Thyroid function in multidrug-resistant tuberculosis patients with or without human immunodeficiency virus (HIV) infection before commencement of MDR-TB drug regimen', African Health Sciences, 16(2), pp. 596–602. DOI: 10.4314/ahs.v16i2.30.

    Kemenkes RI (2013) Cara Penyelenggaraan Laboratorium Klinik yang Baik. Indonesia: Kementerian Kesehatan Republik Indonesia.

    Kemenkes RI (2018) Tuberkulosis ( TB ). 2018th edn, Tuberkulosis. 2018th edn. Jakarta Selatan: PUSAT DATA DAN INFORMASI KEMENTRIAN KESEHATAN RI.

    Kurniawan, L. B. and Arif, M. (2018) ‘DIAGNOSIS TIROID (Diagnosis of Thyroid)’, Indonesian Journal of Clinical Pathology and Medical Laboratory, 21(3), p. 304. doi: 10.24293/ijcpml.v21i3.1285.

    Matveyeva, S. L., Shevchenko, O. S. and Pogorelova, O. O. (2017). 'The function of the thyroid gland in patients with multi-drug resistant tuberculosis', Antimicrobial Resistance and Infection Control, 6(1), pp. 4–6. DOI: 10.1186/s13756-017-0238-4.

    Mustifa and Sugireng (2019) ‘Fungsi ginjal penderita tuberkulosis paru (TB Paru) setelah penggunaan obat anti tuberkulosis kategori 1 (OAT Kat. 1) Di Puskesmas Katobu Kabupaten Muna’, Jurnal MediLab Mandala Waluya kendari, 3(1), pp. 5–48.

    Suparyatmo et al. (2014) ‘Kadar TSH di Multi Drug Resistance Tuberculosis Terkait Etionamid’, Indonesian Journal of Clinical Pathology and Medical Laboratory, 20(3), pp. 238–241. Available at: http://journal.unair.ac.id/download-fullpapers-IJCPML-12-3-08.pdf.

    Varghese, V., Menon, K. S. and Green, S. R. (2018). 'Effect of anti-tuberculosis treatment on thyroid profile in newly detected smear-positive pulmonary tuberculosis cases', Int J Adv Med, 5(3), pp. 688–693. DOI: 10.5005/jp-journals-10085-7166.

    World Health Organization (2021) Global Tuberculosis Report 2021, World Health Organization. Geneva.